I-XW-053

MedChem Express

I-XW-053 [5496-35-5]

5

5496-35-5

Research Use Only

99.71

C22H16N2O2

340.382

I-XW-053 is an inhibitor of HIV-1 capsid protein that can suppress the replication of HIV-189BZ167 with an IC 50 value of 164.2 microM. I-XW-053 exhibits antiviral activity and can block the interface between capsid protein (CA) N-terminal domains (NTD-NTD interface) with micromolar affinity [1] .

O=C(O)C1=CC=C(C2=NC(C3=CC=CC=C3)=C(C4=CC=CC=C4)N2)C=C1

-20°C,2°C to 8°C

12352200