I3MT-3

MedChem Express

I3MT-3 [459420-09-8]

10

459420-09-8

Research Use Only

99.98

C17H14N2O2S

310.37

I3MT-3 (HMPSNE) is a potent, selective, and cell-membrane permeable inhibitor of 3-Mercaptopyruvate sulfurtransferase (3MST) ( IC 50 =2.7 microM). I3MT-3 is inactive for other H2S/sulfane sulfur-producing enzymes.?I3MT-3 targets a persulfurated cysteine residue located in the active site of 3MST [1] .

O=C1NC(SCC(C2=C3C=CC=CC3=CC=C2)=O)=NC(C)=C1

-20°C

12352200