Bio-Connect

IA-14069 [2271216-04-5]

HY-163102
MedChem Express
CAS Number2271216-04-5
Product group Chemicals
Estimated Purity99.93
Molecular Weight392.78
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Overview

  • Supplier
    MedChem Express
  • Product Name
    IA-14069 [2271216-04-5]
  • Delivery Days Customer
    9
  • CAS Number
    2271216-04-5
  • Certification
    Research Use Only
  • Estimated Purity
    99.93
  • Molecular Formula
    C20H15ClF2O4
  • Molecular Weight
    392.78
  • Scientific Description
    IA-14069 is an orally active tumor necrosis factor-alpha (TNF-alpha) inhibitor. IA-14069 binds directly to TNF-alpha and TNF-alpha-triggered signaling (p-IkappaBalpha and NF-kappaB p65) activities. Additionally, IA-14069 exerts a suppressive effect on Dextran sodium sulfate (HY-116282C) (DSS)-induced colitis. IA-14069 can be used for the research of Rheumatoid arthritis (RA) and inflammatory bowel disease (IBD)[1][2].
  • SMILES
    O=C(C1=C(C2=C(F)C=CC(F)=C2)OC3=CC(Cl)=CC=C3C1=O)OC(C)(C)C
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200