Ianalumab [1929549-92-7]

BPS Bioscience

Ianalumab [1929549-92-7]

23

Functional Assay, Flow Cytometry

1929549-92-7

Research Use Only

≥90%

TNFRSF13C

TNF receptor superfamily member 13C

BAFF-R, BAFFR, BROMIX, CD268, CVID4, prolixin, tumor necrosis factor receptor superfamily member 13C, B cell-activating factor receptor, BAFF receptor, BLyS receptor 3

Hamster

IgG1

Tumor necrosis factor receptor superfamily member 13C

Ianalumab, also known as VAY-736, is a human, decarboxylated antibody against BAFF-R. Ianalumab can block the interaction between BAFF and BAFF-R and antagonize the apoptosis protection mediated by BAFF. Ianalumab exerts antibody-dependent cytotoxic (ADCC), depending on effector cell activation mediated by immune receptor tyrosine activation motif (ITAM)1.

-80°C

41116161

Hamster, Human