Ibandronate (Sodium Monohydrate) [138926-19-9]

MedChem Express

Ibandronate (Sodium Monohydrate) [138926-19-9]

10

138926-19-9

Research Use Only

98.0

C9H24NNaO8P2

359.23

Ibandronate Sodium Monohydrate (BM-210955; RPR-102289A) is an orally active, selective inhibitor of farnesyl pyrophosphate synthase (FPP synthase). Ibandronate Sodium Monohydrate can block the mevalonate pathway to inhibit the isoprenylation modification of small GTPases (such as RAS, RHO family proteins), induce tumor cell apoptosis and inhibit bone resorption. Ibandronate Sodium Monohydrate inhibits tumor cell proliferation (such as ER+ breast cancer cells), promotes the expression of the pro-apoptotic gene FAS, and can produce synergistic anti-tumor effects with anti-estrogen compounds. Ibandronate Sodium Monohydrate is used in the study of osteoporosis and bone metastatic tumors (such as breast cancer bone metastasis)[1][2][3][4].

OC(P(O)(O)=O)(P(O)(O[Na])=O)CCN(C)CCCCC.O

2°C to 8°C

12352200