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Iberdomide

M6072
AbMole BioScience
CAS Number1323403-33-3
DownloadDatasheet
Product group Chemicals
Estimated Purity>99%
Molecular Weight449.5
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    Iberdomide
  • Delivery Days Customer
    9
  • CAS Number
    1323403-33-3
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Estimated Purity
    >99%
  • Molecular Formula
    C25H27N3O5
  • Molecular Weight
    449.5
  • Scientific Description
    Iberdomide (CC-220) is an orally effective cereblon (CRBN) E3 ligase modulator (CELMoD) with an IC50 for cereblon binding affinity of approximately 150 nM. Iberdomide (CC-220) binds CRBN with higher affinity than lenalidomide and pomalidomide and has enhanced degradation of IKZF1 and IKZF3 with enhanced degradation.
  • SMILES
    O=C1CCC(N2CC3=C(OCC4=CC=C(CN5CCOCC5)C=C4)C=CC=C3C2=O)C(=O)N1
  • UNSPSC
    12352200