IBL-302 [1414455-21-2]

TargetMol Chemicals

IBL-302 [1414455-21-2]

16

Research Use Only

C25H18FN5O4S3

567.63

IBL-302 (AMU302), an orally available dual-signaling inhibitor targeting PIM and PI3K/AKT/mTOR, is effective against breast cancer and neuroblastoma. It has shown in vivo efficacy in a nude mouse xenograft model by combating trastuzumab resistance. Additionally, IBL-302 augments the effectiveness of widely used cytotoxic chemotherapy drugs such as cisplatin, doxorubicin, and etoposide [1] [2] [3].

CC=1C2=C3C(C=4SC(=CC4)CNC(=O)C=5C=C(S(=O)(=O)NC6=CC(C1S3)=CN=C6OC)C=CC5F)=NC=N2

-20°C

12352200