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IBR2 [313526-24-8]

IBR2 [313526-24-8]

T11600
TargetMol Chemicals
CAS Number313526-24-8
DownloadMSDS
Product group Chemicals
Estimated Purity0.9615
Molecular Weight400.49
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    IBR2 [313526-24-8]
  • Delivery Days Customer
    4
  • CAS Number
    313526-24-8
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    IBR2
  • Estimated Purity
    0.9615
  • Molecular Formula
    C24H20N2O2S
  • Molecular Weight
    400.49
  • Scientific Description
    IBR2 (Isoquinoline) is a potent and specific RAD51 inhibitor known for its ability to suppress RAD51-mediated DNA double-strand break repair. By interfering with RAD51 multimerization, accelerating proteasome-mediated RAD51 protein degradation, inhibiting cancer cell growth, and inducing apoptosis, IBR2 has proved to be an effective compound in these aspects.
  • Shelf life instruction
    3 years
  • SMILES
    O=S(=O)(Cc1ccccc1)N1C=Cc2ccccc2C1c1c[nH]c2ccccc12
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Synthesis, molecular modeling, and biological evaluation of novel RAD51 inhibitors. Zhu J et al., 2015, Eur J Med Chem
    Read more

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