WB analysis of human fetal heart tissue using GTX46887 RNF217 antibody at 0.2-1microg/ml.
WB analysis of human fetal heart tissue using GTX46887 RNF217 antibody at 0.2-1microg/ml.
IBRDC1 antibody, Internal
GTX46887
Overview
- SupplierGeneTex
- Product NameIBRDC1 antibody, Internal
- Delivery Days Customer9
- Application Supplier NoteWB: 0.2-2.5 ug/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.5-1 mg/ml
- ConjugateUnconjugated
- Gene ID154214
- Target nameRNF217
- Target descriptionring finger protein 217
- Target synonymsC6orf172; dJ84N20.1; IBR domain containing 1; IBRDC1; opposite STL; OSTL; probable E3 ubiquitin-protein ligase RNF217
- HostRabbit
- IsotypeIgG
- Protein IDQ8TC41
- Protein NameProbable E3 ubiquitin-protein ligase RNF217
- Scientific DescriptionThis protein encoded by this gene is a member of the RING1-IBR-RING24 (RBR) ubiquitin protein ligase family, and it belongs to a subfamily of these proteins that contain a transmembrane domain. This protein can interact with the HAX1 anti-apoptotic protein via its C-terminal RING finger motif, which suggests a role in apoptosis signaling. It is thought that deregulation of this gene can be a mechanism in leukemogenesis. Mutations in the region encoding the protein GXXXG motif, which appears to be necessary for protein self-association, have been found in human cancers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203