WB analysis of various sample lysates using GTX66301 IBTK antibody. Dilution : 1:1000 Loading : 25microg per lane
WB analysis of various sample lysates using GTX66301 IBTK antibody. Dilution : 1:1000 Loading : 25microg per lane
IBTK antibody
GTX66301
Overview
- SupplierGeneTex
- Product NameIBTK antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500 - 1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID25998
- Target nameIBTK
- Target descriptioninhibitor of Bruton tyrosine kinase
- Target synonymsBruton agammaglobulinemia tyrosine kinase inhibitor; BTBD26; BTK-binding protein; BTKI; inhibitor of Bruton tyrosine kinase; inhibitor of Bruton's tyrosine kinase-alpha; inhibitor of Bruton's tyrosine kinase-beta; inhibitor of Bruton's tyrosine kinase-gamma
- HostRabbit
- IsotypeIgG
- Protein IDQ9P2D0
- Protein NameInhibitor of Bruton tyrosine kinase
- Scientific DescriptionBruton tyrosine kinase (BTK) is a protein tyrosine kinase that is expressed in B cells, macrophages, and neutrophils. The protein encoded by this gene binds to BTK and downregulates BTKs kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription. This gene has a pseudogene on chromosome 18. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203