iC3b

QuidelOrtho

iC3b

7

Other Application

Research Use Only

1 mg/ml

>90%

iC3b is generated during the activation of the complement system via the classical or alternative pathway. When a convertase enzyme cleaves C3, C3a and C3b are released in parallel. In vivo, the C3b molecule has a very short half life; C3b is rapidly cleaved to iC3b which can serve as a marker for complement activation by the alternative or classical pathway. All Quidel complement components are tested for functional activity in a standard lytic or applicable functional assay and for biochemical purity by SDS-polyacrylamide gel electrophoresis. Please refer to the Certificate of Analysis for lot specific information on functional titer. Quidels purified human complement components are useful in a wide variety of immunochemical and research applications. For assistance with a specific protocol, please contact Quidel Technical Support.

-80°C

12352202