Chemical Structure
Chemical Structure
IC87114
SYN-1045
CAS Number371242-69-2
Product group Chemicals
Estimated Purity>95%
Molecular Weight397.4
Overview
- SupplierSYNkinase
- Product NameIC87114 [371242-69-2]
- Delivery Days Customer10
- CAS Number371242-69-2
- CertificationResearch Use Only
- Estimated Purity>95%
- Hazard InformationWarning
- Molecular FormulaC22H19N7O
- Molecular Weight397.4
- Scientific DescriptionChemical. CAS: 371242-69-2. Formula: C22H19N7O. MW: 397.4. IC87114 is a potent, ATP-competitive, and selective inhibitor of PI3Kdelta. IC(50) values (130-500nM) for IC87114 are sub-micromolar over a wide range of ATP concentrations from 10microM to 200microM. IC87114 can selectively inhibit cellular migration but not adhesion as well as cellular polarization. More recent work has shown the PIK3delta inhibition also plays a role in autoimmune disease suppression. - IC87114 is a potent, ATP-competitive, and selective inhibitor of PI3Kdelta. IC(50) values (130-500nM) for IC87114 are sub-micromolar over a wide range of ATP concentrations from 10microM to 200microM. IC87114 can selectively inhibit cellular migration but not adhesion as well as cellular polarization. More recent work has shown the PIK3delta inhibition also plays a role in autoimmune disease suppression.
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC51202000
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![IC-87114 [371242-69-2]](https://www.targetmol.com/group3/M00/35/44/CgoaEGayGl2ED1GdAAAAAILZowY251.png)
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