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ProductsBack/IC87114 [371242-69-2]
Chemical Structure
Chemical Structure
Chemical Structure

IC87114 [371242-69-2]

SYN-1045
SYNkinase
CAS Number371242-69-2
Product group Chemicals
Estimated Purity>95%
Molecular Weight397.4
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Overview

  • Supplier
    SYNkinase
  • Product Name
    IC87114 [371242-69-2]
  • Delivery Days Customer
    10
  • CAS Number
    371242-69-2
  • Certification
    Research Use Only
  • Estimated Purity
    >95%
  • Hazard Information
    Warning
  • Molecular Formula
    C22H19N7O
  • Molecular Weight
    397.4
  • Scientific Description
    Chemical. CAS: 371242-69-2. Formula: C22H19N7O. MW: 397.4. IC87114 is a potent, ATP-competitive, and selective inhibitor of PI3Kdelta. IC(50) values (130-500nM) for IC87114 are sub-micromolar over a wide range of ATP concentrations from 10microM to 200microM. IC87114 can selectively inhibit cellular migration but not adhesion as well as cellular polarization. More recent work has shown the PIK3delta inhibition also plays a role in autoimmune disease suppression. - IC87114 is a potent, ATP-competitive, and selective inhibitor of PI3Kdelta. IC(50) values (130-500nM) for IC87114 are sub-micromolar over a wide range of ATP concentrations from 10microM to 200microM. IC87114 can selectively inhibit cellular migration but not adhesion as well as cellular polarization. More recent work has shown the PIK3delta inhibition also plays a role in autoimmune disease suppression.
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    51202000