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ICA-069673

HY-101396
MedChem Express
CAS Number582323-16-8
DownloadMSDS
Product group Chemicals
Estimated Purity99.65
Molecular Weight269.63
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Overview

  • Supplier
    MedChem Express
  • Product Name
    ICA-069673 [582323-16-8]
  • Delivery Days Customer
    10
  • CAS Number
    582323-16-8
  • Certification
    Research Use Only
  • Estimated Purity
    99.65
  • Molecular Formula
    C11H6ClF2N3O
  • Molecular Weight
    269.63
  • Scientific Description
    ICA-069673 is a KCNQ2/Q3 potassium channel activator. ICA-069673 demonstrates greater selectivity for KV7.2/7.3 over KV7.3/KV7.5 , with EC 50 s of 0.69 microM and 14.3 microM, respectively. ICA-069673 inhibits spontaneous phasic and nerve-evoked contractions in guinea pig detrusor smooth muscle (DSM). ICA-069673 also decreases the global intracellular Ca(2+) concentration in DSM cells [1] [2] .
  • SMILES
    O=C(NC1=CN=C(Cl)N=C1)C2=CC=C(F)C(F)=C2
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200