More than 130 suppliers
ISO certified
In-house tech support
we Connect you
Bio-Connect
ProductsBack/ICA-121431 [313254-51-2]

ICA-121431 [313254-51-2]

Research Use Only
HY-16787
MedChem Express
CAS Number313254-51-2
DownloadMSDS
Product group Chemicals
Estimated Purity98.65
Molecular Weight449.55
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request
More than 130 suppliers
ISO certified
In-house tech support

Overview

  • Supplier
    MedChem Express
  • Product Name
    ICA-121431 [313254-51-2]
  • Delivery Days Customer
    10
  • CAS Number
    313254-51-2
  • Certification
    Research Use Only
  • Estimated Purity
    98.65
  • Molecular Formula
    C23H19N3O3S2
  • Molecular Weight
    449.55
  • Scientific Description
    ICA-121431 is a nanomolar potent and broad-spectrum voltage-gated sodium channel (Nav) blocker, shows equipotent selectivity for human Nav1.1 and Nav1.3 subtypes with IC50 values of 13 nM and 23 nM, respectively. ICA-121431 shows less potent inhibition of Nav1.2 (IC50=240 nM) and 1,000 fold selectivity against Nav1.4, Nav1.6, and the TTX-resistant human Nav1.5 and Nav1.8 channels (IC50s >10 microM).
  • SMILES
    O=C(NC1=CC=C(S(NC2=NC=CS2)(=O)=O)C=C1)C(C3=CC=CC=C3)C4=CC=CC=C4
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200