ICA-27243

MedChem Express

ICA-27243 [325457-89-4]

10

325457-89-4

Research Use Only

99.27

C12H7ClF2N2O

268.65

ICA-27243 is a selective, potent and orally active KCNQ2/Q3 potassium channel opener with an EC50 of 0.38 microM. ICA-27243 is less effective at activating KCNQ4 and KCNQ3/Q5. ICA-27243 has antiepileptic and anticonvulsant effects[1][2].

O=C(C1=CC=C(C(F)=C1)F)NC2=CC=C(N=C2)Cl

-20°C,2°C to 8°C

12352200