ICAM3 antibody [SPM505]

GeneTex

ICAM3 antibody [SPM505]

9

Recognizes the D1 domain of an N-glycosylated glycoprotein of 120kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3.

WB: 1-2microg/ml. ICC/IF: 1-2microg/ml. IHC-P: 1-2microg/ml for 30 minutes at RT. FACS: 1-2microg/106 cells. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

SPM505

0.2 mg/ml

Unconjugated

ICAM3

intercellular adhesion molecule 3

CD50; CDW50; ICAM-3; ICAM-R; intercellular adhesion molecule 3

Mouse

IgG2b

Intercellular adhesion molecule 3

The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016]

Human

-20°C or -80°C,2°C to 8°C

12352203