ICCB280 [2041072-41-5]

MedChem Express

ICCB280 [2041072-41-5]

10

2041072-41-5

Research Use Only

98.14

C23H18N2O4

386.40

ICCB280 is a potent inducer of C/EBPalpha. ICCB280 exhibits anti-leukemic properties including terminal differentiation, proliferation arrest, and apoptosis through activation of C/EBPalpha and affecting its downstream targets (such as C/EBPepsilon, G-CSFR and c-Myc)[1][2].

O=C1N(C2=CC=CC=C2OC)C(/C=C/C3=CC=C(O)C(O)=C3)=NC4=C1C=CC=C4

-20°C

12352200