ICG-001

MedChem Express

ICG-001 [780757-88-2]

10

780757-88-2

Research Use Only

99.86

C33H32N4O4

548.63

ICG-001 is an inhibitor of beta-catenin/TCF mediated transcription. ICG-001 works by specifically binding to cyclic AMP response element-binding protein with an IC50 of 3 microM. ICG-001 selectively blocks the beta-catenin/CBP interaction without interfering with the beta-catenin/p300 interaction.

O=C(NCC1=CC=CC=C1)N2CCC(N([C@@]2(CN(C3=O)CC4=C5C=CC=CC5=CC=C4)[H])[C@H]3CC6=CC=C(C=C6)O)=O

-20°C,2°C to 8°C

12352200