ICMT-IN-54 [908856-14-4]

MedChem Express

ICMT-IN-54 [908856-14-4]

14

908856-14-4

Research Use Only

C29H45NO3S

487.74

ICMT-IN-54 (compound 7c) is an adamantyl analogue and an ICMT inhibitor (IC50=12.4 microM), which can inhibit ICMT Methylation. ICMT-in-54 inhibits BFC (N-biotinyl-(6-aminohexanoic)-S-farnesyl-L-cysteine) methylation in saccharomyces cerevisiae expressing ICMT, which is an indirect effect of inhibiting ICMT methylation[1].

C/C(C)=C/CC/C(C)=C/CC/C(C)=C/CSC[C@@H](C(O)=O)NC(C12CC3CC(CC(C3)C2)C1)=O

12131703