Icotinib-d4 [1567366-82-8]
HY-15164AS
Overview
- SupplierMedChem Express
- Product NameIcotinib-d4 [1567366-82-8]
- Delivery Days Customer14
- CAS Number1567366-82-8
- CertificationResearch Use Only
- Molecular FormulaC22H17D4N3O4
- Molecular Weight395.44
- Scientific DescriptionIcotinib-d4 is the deuterium-labeled Icotinib (HY-15164A). Icotinib-d4 (BPI-2009) is a potent and specific EGFR inhibitor with an IC50 of 5 nM; also inhibits mutant EGFRL858R, EGFRL858R/T790M, EGFRT790M and EGFRL861Q. Icotinib-d4 is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- SMILES[2H]C1([2H])C([2H])([2H])OCCOC2=CC(C(NC3=CC(C#C)=CC=C3)=NC=N4)=C4C=C2OCCO1
- UNSPSC12131703