ID4 antibody - middle region

Aviva Systems Biology

ID4 antibody - middle region

23

Western Blot

Research Use Only

Polyclonal

0.5 mg/ml

ID4

inhibitor of DNA binding 4

IDB4, bHLHb27, DNA-binding protein inhibitor ID-4, class B basic helix-loop-helix protein 27, inhibitor of DNA binding 4, HLH protein, inhibitor of DNA binding 4, dominant negative helix-loop-helix protein, inhibitor of differentiation 4

Rabbit

DNA-binding protein inhibitor ID-4

Transcription factors containing a basic helix-loop-helix (bHLH) motif regulate expression of tissue-specific genes in a number of mammalian and insect systems. DNA-binding activity of the bHLH proteins is dependent on formation of homo- and/or heterodimers. Dominant-negative HLH proteins encoded by Id-related genes, such as ID4, also contain the HLH-dimerization domain but lack the DNA-binding basic domain. Consequently, Id proteins inhibit binding to DNA and transcriptional transactivation by heterodimerization with bHLH proteins.Transcription factors containing a basic helix-loop-helix (bHLH) motif regulate expression of tissue-specific genes in a number of mammalian and insect systems. DNA-binding activity of the bHLH proteins is dependent on formation of homo- and/or heterodimers. Dominant-negative HLH proteins encoded by Id-related genes, such as ID4, also contain the HLH-dimerization domain but lack the DNA-binding basic domain. Consequently, Id proteins inhibit binding to DNA and transcriptional transactivation by heterodimerization with bHLH proteins (Pagliuca et al., 1995 [PubMed 7665172]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

-20°C,2°C to 8°C

41116161