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IDE1 [1160927-48-9]

Research Use Only
T3162
TargetMol Chemicals
CAS Number1160927-48-9
DownloadMSDS
Product group Chemicals
Molecular Weight306.31
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    IDE1 [1160927-48-9]
  • Delivery Days Customer
    9
  • CAS Number
    1160927-48-9
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    IDE1
  • Molecular Formula
    C15H18N2O5
  • Molecular Weight
    306.31
  • Scientific Description
    IDE1 can induce definitive endoderm from embryonic stem cells. It has been shown to induce the differentiation of Sox17+/FoxA2+-expressing pancreatic progenitors from human and mouse embryonic stems cells (EC50: 125.5 nM in vitro) by activating the TGF-beta signaling pathway. IDE1-derived endodermal cells injected into E8.75 mouse embryos ex vivo have been shown to incorporate into the developing gut tube, contributing to its formation.
  • Shelf life instruction
    3 years
  • SMILES
    C(=NNC(CCCCCC(O)=O)=O)C1=C(C(O)=O)C=CC=C1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Hoveizi E, et al. Definitive endoderm differentiation of human-induced pluripotent stem cells using signaling molecules and IDE1 in three-dimensional polymer scaffold. J Biomed Mater Res A. 2014 Nov;102(11):4027-36.
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