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ProductsBack/Idebenone-13C,d3 [1189907-75-2]

Idebenone-13C,d3 [1189907-75-2]

HY-W777283
MedChem Express
CAS Number1189907-75-2
Product group Chemicals
Molecular Weight342.45
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Idebenone-13C,d3 [1189907-75-2]
  • Delivery Days Customer
    999
  • CAS Number
    1189907-75-2
  • Certification
    Research Use Only
  • Molecular Formula
    C18 13CH27D3O5
  • Molecular Weight
    342.45
  • Scientific Description
    Idebenone-13C,d3 is the deuterium labeled and 13C-labeled Idebenone (HY-N0303). Idebenone, a well-appreciated mitochondrial protectant, exhibits protective efficacy against neurotoxicity and can be used for the research of Alzheimers disease, Huntingtons disease. Idebenone (oxidised form) has a dose-dependent inhibitory effect on the enzymatic metabolism of arachidonic acid in astroglial homogenates (IC50=16.65 microM)[1]. Idebenone, a coenzyme Q10 analog and an antioxidant, induces apoptotic cell death in the human dopaminergic neuroblastoma SHSY-5Y cells[2]. Idebenone quickly crosses the blood-brain barrier.
  • SMILES
    O=C(C(CCCCCCCCCCO)=C(C1=O)C)C(OC)=C1O[13C]([2H])([2H])[2H]
  • UNSPSC
    12352200

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