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IDH1 Inhibitor 1 [2234285-81-3]

HY-112601
MedChem Express
CAS Number2234285-81-3
Product group Chemicals
Estimated Purity99.96
Molecular Weight450.39
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Overview

  • Supplier
    MedChem Express
  • Product Name
    IDH1 Inhibitor 1 [2234285-81-3]
  • Delivery Days Customer
    10
  • CAS Number
    2234285-81-3
  • Certification
    Research Use Only
  • Estimated Purity
    99.96
  • Molecular Formula
    C20H18F4N6O2
  • Molecular Weight
    450.39
  • Scientific Description
    IDH1 Inhibitor 1 is a potent, orally bioavailable, brain-penetrant and selective mutant IDH1 inhibitor with IC50s of 0.021 microM, 0.045 microM, and 2.52 microM for IDH1R132H, IDH1R132C, and IDH1WT, respectively[1]. Anticancer activity[1].
  • SMILES
    C[C@H](NC1=NC(N2[C@@H](CF)COC2=O)=CC=N1)C(N=C3)=CN3C4=CC=C(C(F)(F)F)C=C4
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12131703

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