IDH2 antibody
GTX133078
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
TargetIDH2
Overview
- SupplierGeneTex
- Product NameIDH2 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.33 mg/ml
- ConjugateUnconjugated
- Gene ID3418
- Target nameIDH2
- Target descriptionisocitrate dehydrogenase (NADP(+)) 2
- Target synonymsD2HGA2, ICD-M, IDH, IDH-2, IDHM, IDP, IDPM, mNADP-IDH, isocitrate dehydrogenase [NADP], mitochondrial, NADP(+)-specific ICDH, isocitrate dehydrogenase (NADP(+)) 2, mitochondrial, isocitrate dehydrogenase 2 (NADP+), mitochondrial, oxalosuccinate decarboxylase
- HostRabbit
- IsotypeIgG
- Protein IDP48735
- Protein NameIsocitrate dehydrogenase [NADP], mitochondrial
- Scientific DescriptionIsocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Avolio R, Agliarulo I, Criscuolo D, et al. Cytosolic and mitochondrial translation elongation are coordinated through the molecular chaperone TRAP1 for the synthesis and import of mitochondrial proteins. Genome Res. 2023,33(8):1242-1257. doi: 10.1101/gr.277755.123Read this paper
- Avolio R, Agliarulo I, Criscuolo D, et al. Cytosolic and mitochondrial translation elongation are coordinated through the molecular chaperone TRAP1 for the synthesis and import of mitochondrial proteins. bioRxiv. 2023,:pii: 2023.01.19.524708. doi: 10.1101/2023.01.19.524708.Read this paper






