IDH2-C100, IHD2 Inhibitor

Bioss

IDH2-C100, IHD2 Inhibitor [1446506-78-0]

16

Research Use Only

98.0

IDH2-C100 is a potent and selective inhibitor of IDH2 R140Q and R172K mutant first reported in patent WO 2013102431. It can inhibit the enzymatic activity of IDH2 R140Q and R172K in vitro with an IC50 < 0.1 microM. It has IC50 < 0.1 microM in U87MG pLVX-IDH2 R140Q-neo cell based assay. It is an analog of clinical IDH2 inhibitor AG-221 by Thomson Reuters Integrity analysis.

-20°C

51202000