IDO1 antibody
GTX113753
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityHuman, Rat
TargetIDO1
Overview
- SupplierGeneTex
- Product NameIDO1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID3620
- Target nameIDO1
- Target descriptionindoleamine 2,3-dioxygenase 1
- Target synonymsIDO; IDO-1; INDO; indolamine 2,3 dioxygenase; indole 2,3-dioxygenase; indoleamine 2,3-dioxygenase 1; indoleamine-pyrrole 2,3-dioxygenase
- HostRabbit
- IsotypeIgG
- Protein IDP14902
- Protein NameIndoleamine 2,3-dioxygenase 1
- Scientific DescriptionGamma-interferon (IFNG; MIM 147570) has an antiproliferative effect on many tumor cells and inhibits intracellular pathogens such as Toxoplasma and Chlamydia, at least partly because of the induction of indoleamine 2,3-dioxygenase (INDO; EC 1.13.11.52). This enzyme catalyzes the degradation of the essential amino acid L-tryptophan to N-formyl-kynurenine.[supplied by OMIM]
- ReactivityHuman, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Tryptophan Depletion Modulates Tryptophanyl-tRNA Synthetase-Mediated High-Affinity Tryptophan Uptake into Human Cells. Yokosawa T et al., 2020 Nov 27, Genes (Basel)Read more
- MLLT6 maintains PD-L1 expression and mediates tumor immune resistance. Sreevalsan S et al., 2020 Dec 3, EMBO RepRead more
- Role of indoleamine 2,3-dioxygenase in testicular immune-privilege. Gualdoni GS et al., 2019 Nov 4, Sci RepRead more
- Intestine-Specific Homeobox Gene ISX Integrates IL6 Signaling, Tryptophan Catabolism, and Immune Suppression. Wang LT et al., 2017 Aug 1, Cancer ResRead more