IDO/Tubulin-IN-2 [2409479-24-7]

MedChem Express

IDO/Tubulin-IN-2 [2409479-24-7]

10

2409479-24-7

Research Use Only

C48H40N6O10

860.87

IDO/Tubulin-IN-2 (HT2) is a potent TDO and tubulin inhibitor. IDO/Tubulin-IN-2 also shows potent activity against U87, HepG2, A549, HCT-116, and LO2 cancer cell lines, with IC50 values of 0.43, 0.036, 0.041, 0.095 and 1.04 microM, respectively. IDO/Tubulin-IN-2 remarkably promotes the antitumor activity[1].

COC1=CC=C(C=C1OC(C2=CC=CC(CN3C=C(N=N3)CCOC(C4=CC=CC(CN5N=NC6=C5C(C7=CC=CC=C7C6=O)=O)=C4)=O)=C2)=O)/C=C\C8=CC(OC)=C(C(OC)=C8)OC

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