Idoxuridine

MedChem Express

Idoxuridine [54-42-2]

10

54-42-2

Research Use Only

99.95

C9H11IN2O5

354.10

Idoxuridine (5-Iodo-2-deoxyuridine, 5-IUdR, IdUrd) is an iodinated thymidine analogue that competitively inhibits phosphorylases . Idoxuridine can inhibit viral activity, particularly viral eye infections, including herpes simplex keratitis, by inhibiting DNA polymerase and affecting viral replication. Idoxuridine against feline herpesvirus has the IC 50 value of 4.3 microM [1] . Idoxuridine shows anti-orthopoxvirus activity.

O=C(N1)N([C@H]2C[C@H](O)[C@@H](CO)O2)C=C(I)C1=O

-20°C,2°C to 8°C

12352200