
Immunofluorescent analysis of MCF-7 cells using CSB-PA011002LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
IER3 Antibody
CSB-PA011002LA01HU
ApplicationsImmunoFluorescence, ELISA
Product group Antibodies
ReactivityHuman
TargetIER3
Overview
- SupplierCusabio
- Product NameIER3 Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID8870
- Target nameIER3
- Target descriptionimmediate early response 3
- Target synonymsanti-death protein; DIF2; DIF-2; differentiation-dependent gene 2 protein; expressed in pancreatic carcinoma; GLY96; gly96, mouse, homolog of; IEX1; IEX-1; IEX-1L; immediate early protein GLY96; immediate early response 3 protein; immediately early gene X-1; PACAP-responsive gene 1 protein; PRG1; protein DIF-2; radiation-inducible immediate-early gene IEX-1
- HostRabbit
- IsotypeIgG
- Protein IDP46695
- Protein NameRadiation-inducible immediate-early gene IEX-1
- Scientific DescriptionMay play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A-PPP2R5C holoenzyme. Acts also as an ERK downstream effector mediating survival. As a member of the NUPR1/RELB/IER3 survival pathway, may provide pancreatic ductal adenocarcinoma with remarkable resistance to cell stress, such as starvation or gemcitabine treatment.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203