Ifenprodil (tartrate) [23210-58-4]

MedChem Express

Ifenprodil (tartrate) [23210-58-4]

10

23210-58-4

Research Use Only

99.95

C21H27NO2.1/2C4H6O6

400.49

Ifenprodil (NP-120) tartrate, a cerebral vasodilator, is a noncompetitive NMDA receptor antagonist. Ifenprodil tartrate exerts high affinity at NR1A/NR2B receptors (IC50=0.34 microM) over 400-fold than at NR1A/NR2A receptors (IC50=146 microM)[1]. Ifenprodil tartrate is an alpha1 adrenergic receptor antagonist. Ifenprodil tartrate inhibits GIRK (Kir3), reduces inward currents through the basal GIRK activity. Ifenprodil tartrate has reliable inhibitory effects against A/H1N1 strains (EC50 of 6.6 microM). Ifenprodil tartrate has neuroprotective, anticonvulsant and antinociceptive effects. Ifenprodil tartrate can be used for the study of cerebrovascular diseases and peripheral arterial obliterative disease[2][4].

OC(C1=CC=C(O)C=C1)C(C)N(CC2)CCC2CC3=CC=CC=C3.O=C(O)[C@H](O)[C@@H](O)C(O)=O.[1/2]

2°C to 8°C

12352200