IFIT2 Antibody

Cusabio

IFIT2 Antibody

20

ImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

IFIT2

interferon induced protein with tetratricopeptide repeats 2

G10P2, GARG-39, IFI-54, IFI-54K, IFI54, IFIT-2, ISG-54, ISG-54 K, ISG-54K, ISG54, P54, cig42, interferon-induced protein with tetratricopeptide repeats 2, Interferon, alpha-inducible protein (MW 54kD), interferon-induced 54 kDa protein, interferon-induced protein 54

Rabbit

IgG

Interferon-induced protein with tetratricopeptide repeats 2

IFN-induced antiviral protein which inhibits expression of viral messenger RNAs lacking 2-O-methylation of the 5 cap. The ribose 2-O-methylation would provide a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Viruses evolved several ways to evade this restriction system such as encoding their own 2-O-methylase for their mRNAs or by stealing host cap containing the 2-O-methylation (cap snatching mechanism). Binds AU-rich viral RNAs, with or without 5 triphosphorylation, RNA-binding is required for antiviral activity. Can promote apoptosis.

Human, Rat

-20°C or -80°C

41116161