
Western Blot Positive WB detected in: HEK293 whole cell lysate, Rat liver tissue All lanes: IFIT2 antibody at 3microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 55 kDa Observed band size: 55 kDa
IFIT2 Antibody
CSB-PA011021LA01HU
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Rat
TargetIFIT2
Overview
- SupplierCusabio
- Product NameIFIT2 Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID3433
- Target nameIFIT2
- Target descriptioninterferon induced protein with tetratricopeptide repeats 2
- Target synonymscig42; G10P2; GARG-39; IFI54; IFI-54; IFI-54K; IFIT-2; Interferon, alpha-inducible protein (MW 54kD); interferon-induced 54 kDa protein; interferon-induced protein 54; interferon-induced protein with tetratricopeptide repeats 2; ISG54; ISG-54; ISG-54 K; ISG-54K; P54
- HostRabbit
- IsotypeIgG
- Protein IDP09913
- Protein NameInterferon-induced protein with tetratricopeptide repeats 2
- Scientific DescriptionIFN-induced antiviral protein which inhibits expression of viral messenger RNAs lacking 2-O-methylation of the 5 cap. The ribose 2-O-methylation would provide a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Viruses evolved several ways to evade this restriction system such as encoding their own 2-O-methylase for their mRNAs or by stealing host cap containing the 2-O-methylation (cap snatching mechanism). Binds AU-rich viral RNAs, with or without 5 triphosphorylation, RNA-binding is required for antiviral activity. Can promote apoptosis.
- ReactivityHuman, Rat
- Storage Instruction-20°C or -80°C
- UNSPSC41116161