IFITM2 Antibody, Biotin conjugated

Cusabio

IFITM2 Antibody, Biotin conjugated

20

ELISA

Research Use Only

Polyclonal

Biotin

IFITM2

interferon induced transmembrane protein 2

1-8D, DSPA2c, interferon-induced transmembrane protein 2, dispanin subfamily A member 2c, interferon-inducible protein 1-8D

Rabbit

IgG

Interferon-induced transmembrane protein 2

IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry. Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner.

Human

-20°C or -80°C

41116161