iFluor(tm) 488 Conjugated Anti-Iba1 Antibody [JM36-62]
HA720158F
ApplicationsFlow Cytometry, ImmunoFluorescence
Product group Antibodies
TargetAIF1
Overview
- SupplierHUABIO
- Product NameiFluor(tm) 488 Conjugated Anti-Iba1 Antibody [JM36-62]
- Delivery Days Customer2
- ApplicationsFlow Cytometry, ImmunoFluorescence
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDJM36-62
- Concentration1 mg/ml
- ConjugateOther Conjugate
- Gene ID199
- Target nameAIF1
- Target descriptionallograft inflammatory factor 1
- Target synonymsAIF-1, IBA1, IRT-1, IRT1, allograft inflammatory factor 1, interferon gamma responsive transcript, ionized calcium-binding adapter molecule 1, protein G1
- HostRabbit
- IsotypeIgG
- Protein IDO70200
- Protein NameAllograft inflammatory factor 1
- Scientific DescriptionIonized calcium-binding adapter molecule 1 (Iba1), also known as allograft inflammatory factor-1 (AIF-1), is a 147 amino acid cytoplasmic, calcium-binding protein that is thought to play a role in macrophage activation and function. Iba1, containing two EF domains, is induced by cytokines and interferons. In an unstimulated state, Iba1 colocalizes with actin, and upon stimulation, translocates to lamellipodia. It is also a marker of human microglia and is expressed by macrophages in injured skeletal muscle. The gene encoding Iba1 maps to chromosome 6p21.33 and resides in the tumor necrosis factor (TNF) cluster of genes located in the region represented by the human major histocompatibility complex (MHC).
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC41116161