iFluor(tm) 647 Conjugated Anti-Human CD14 Antibody [SC69-02]
HA720184F
ApplicationsFlow Cytometry
Product group Antibodies
TargetCD14
Overview
- SupplierHUABIO
- Product NameiFluor(tm) 647 Conjugated Anti-Human CD14 Antibody [SC69-02]
- Delivery Days Customer2
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDSC69-02
- Concentration1 mg/ml
- ConjugateOther Conjugate
- Gene ID929
- Target nameCD14
- Target descriptionCD14 molecule
- Target synonymsmonocyte differentiation antigen CD14, my23 antigen, myeloid cell-specific leucine-rich glycoprotein
- HostRabbit
- IsotypeIgG
- Protein IDP08571
- Protein NameMonocyte differentiation antigen CD14
- Scientific DescriptionLipopolysaccharide (LPS) elicits the secretion of mediators and cytokines produced by activated macrophages and monocytes. CD14 is a glycosylphosphatidylinositol (GPI)-anchored protein found on the surfaces of monocytes and polymorphonuclear leukocytes. CD14 functions as a receptor for LPS, resulting in the secretion of various proteins. An important component in the LPS activation of monocytes through the CD14 receptor is the adapter molecule, lipopolysaccharide binding protein (LBP). There are two forms of CD14, a membrane-associated form (mCD14), and a soluble form (sCD14). mCD14 responds to LPS alone and facilitates the secretion of proteins, while cells not expressing mCD14 fail to respond to LPS. The cells that lack mCD14 respond to LPS/LBP in the presence of sCD14.
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC41116161