IFN-beta, Human (CHO)

MedChem Express

IFN-beta, Human (CHO)

10

Research Use Only

98.0

IFNB1

interferon beta 1

fibroblast interferon; IFB; IFF; IFNB; IFN-beta; interferon beta; interferon, beta 1, fibroblast; interferon-beta

Interferon beta

IFN-beta is a secretory cytokine produced by cells under viral infection or nucleic acid stimulation. IFNbeta binds to cell surface heterodimeric receptors (IFNAR1/IFNAR2), activates the JAK-STAT signaling pathway, and induces the expression of interferon-stimulated genes (ISGs) (such as PKR, 25-OAS). IFN-beta inhibits viral proliferation, regulates immune responses (such as inhibiting Th1 cell polarization, reducing pro-inflammatory cytokine secretion), inhibits the proliferation of vascular smooth muscle cells and tumor cells. IFN-beta has anti-atherosclerotic and vascular remodeling effects. IFN-beta Protein, Human (CHO) is a recombinant interferon-beta protein (CHO), expressed by CHO, without a tag.

-20°C

41116100