IFNAR1, Mouse (HEK293, His)

MedChem Express

IFNAR1, Mouse (HEK293, His)

10

Research Use Only

95.0

Ifnar1

interferon (alpha and beta) receptor 1

I; If; Ifar; IFN-alpha/beta receptor 1; IFN-alpha/betaR; Ifnar; IFN-R-1; Ifrc; INF-a receptor; Infar; interferon alpha/beta receptor 1; type I interferon receptor 1

Interferon alpha/beta receptor 1

IFNAR1, one of the subunit of IFN-alpha/beta receptor, is a type I IFN receptor. IFNAR1 forms the heterodimeric receptor with IFNAR2. IFNAR1 mediates IFN-induced STAT signaling by interacting with tyrosine kinase 2 (Tyk2)[1][2]. Upon activation by these IFNs, IFNAR1 and IFNAR2 undergo a conformational change to promote a cascade of downstream signaling events, including the phosphorylation of Tyk2 and JAK1, STAT1 and STAT2[3]. IFNAR1 Protein, Mouse (HEK293, His) is a recombinant mouse IFNAR1 (M1-T429) with C-terminal His tag, which is produced in HEK293 cells.

-20°C

41116100