IFNAR1, Rhesus Macaque (HEK293)

MedChem Express

IFNAR1, Rhesus Macaque (HEK293)

5

Research Use Only

96.00

IFNAR1

interferon alpha and beta receptor subunit 1

interferon alpha/beta receptor 1

Interferon alpha/beta receptor 1

IFNAR1, one of the subunit of IFN-alpha/beta receptor, is a type I IFN receptor. IFNAR1 forms the heterodimeric receptor with IFNAR2. IFNAR1 mediates IFN-induced STAT signaling by interacting with tyrosine kinase 2 (Tyk2)[1][2]. Upon activation by these IFNs, IFNAR1 and IFNAR2 undergo a conformational change to promote a cascade of downstream signaling events, including the phosphorylation of Tyk2 and JAK1, STAT1 and STAT2[3]. IFNAR1 Protein, Rhesus Macaque (HEK293) is a recombinant rhesus macaque IFNAR1 (M1-K437) without any tag, which is produced in HEK293 cells.

-20°C

41116100

Primate