IGF-I R, Human (HEK293, Fc)
HY-P704676
Protein IDP08069
Product group Proteins / Signaling Molecules
Overview
- SupplierMedChem Express
- Product NameIGF-I R, Human (HEK293, Fc)
- Delivery Days Customer999
- CertificationResearch Use Only
- Gene ID3480
- Target nameIGF1R
- Target descriptioninsulin like growth factor 1 receptor
- Target synonymsCD221, IGFIR, IGFR, JTK13, insulin-like growth factor 1 receptor, IGF-I receptor
- Protein IDP08069
- Protein NameInsulin-like growth factor 1 receptor
- Scientific DescriptionIGF-I receptor (IGF1R) mediates insulin-like growth factor effects, binding strongly to IGF1. Activation triggers PI3K-AKT/PKB and Ras-MAPK pathways, influencing cell survival, protein synthesis, and proliferation. IGF1R also signals through JAK/STAT, inhibiting JNK activation. Hybrid receptors show variable binding to IGF1 and insulin. IGF-I R Protein, Human (HEK293, Fc) is the recombinant human-derived IGF-I R protein, expressed by HEK293, with C-hFc labeled tag.
- UNSPSC41116100
- SpeciesHuman