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IGF-I R, Human (HEK293, His, solution)

HY-P74442
MedChem Express
Protein IDP08069
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    MedChem Express
  • Product Name
    IGF-I R, Human (HEK293, His, solution)
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Estimated Purity
    95.0
  • Protein IDP08069
  • Protein Name
    Insulin-like growth factor 1 receptor
  • Scientific Description
    IGF-I receptor (IGF1R) mediates insulin-like growth factor effects, binding strongly to IGF1. Activation triggers PI3K-AKT/PKB and Ras-MAPK pathways, influencing cell survival, protein synthesis, and proliferation. IGF1R also signals through JAK/STAT, inhibiting JNK activation. Hybrid receptors show variable binding to IGF1 and insulin. IGF-I R Protein, Human (HEK293, His, solution) is the recombinant human-derived IGF-I R protein, expressed by HEK293 , with C-His labeled tag.
  • Storage Instruction
    -80°C
  • UNSPSC
    12352202

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