More than 130 suppliers
ISO certified
In-house tech support
we Connect you
Bio-Connect
ProductsBack/IGF1R beta antibody
ICC/IF analysis of methanol-fixed MCF cells using GTX50433 IGF1R beta antibody.
ICC/IF analysis of methanol-fixed MCF cells using GTX50433 IGF1R beta antibody.
ICC/IF analysis of methanol-fixed MCF cells using GTX50433 IGF1R beta antibody.

IGF1R beta antibody

GTX50433
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetIGF1R
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request
More than 130 suppliers
ISO certified
In-house tech support

Overview

  • Supplier
    GeneTex
  • Product Name
    IGF1R beta antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:1000. ICC/IF: 1:100-1:200. IHC-P: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3480
  • Target name
    IGF1R
  • Target description
    insulin like growth factor 1 receptor
  • Target synonyms
    CD221, IGFIR, IGFR, JTK13, insulin-like growth factor 1 receptor, IGF-I receptor
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP08069
  • Protein Name
    Insulin-like growth factor 1 receptor
  • Scientific Description
    This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Chiu YF, Wu CC, Kuo MH, et al. Critical role of SOX2-IGF2 signaling in aggressiveness of bladder cancer. Sci Rep. 2020,10(1):8261. doi: 10.1038/s41598-020-65006-z
    Read this paper
  • Wu SG, Chang TH, Tsai MF, et al. IGFBP7 Drives Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibition in Lung Cancer. Cancers (Basel). 2019,11(1). doi: 10.3390/cancers11010036
    Read this paper

Datasheet

Download Datasheet

FAQ

Go to our frequently asked questions

Related products

Product group Antibodies
Biosynth
IGF-1R antibody20R-2261
  • SizePrice
Product group Antibodies
Absolute Antibody
Anti-IGF-1 [7973 [M23]], Mouse IgG1, kappaAB04263-1.1
ApplicationsWestern Blot, ImmunoHistoChemistry
ReactivityHuman, Mouse, Rat
TargetIGF1R
  • SizePrice
Figure 1. Western blot analysis of IGF1R using anti-IGF1R antibody (A00070-3). Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 30 ug of sample under reducing conditions. Lane 1: human Hela whole cell lysates, Lane 2: human MCF-7 whole cell lysates, Lane 3: human SH-SY5Y whole cell lysates, Lane 4: human A549 whole cell lysates. After electrophoresis, proteins were transferred to a nitrocellulose membrane at 150 mA for 50-90 minutes. Blocked the membrane with 5% non-fat milk/TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-IGF1R antigen affinity purified polyclonal antibody (Catalog # A00070-3) at 0.5 microg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:5000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for IGF1R at approximately 110,200 kDa. The expected band size for IGF1R is at 155 kDa.
Product group Antibodies
Boster Bio
Anti-IGF1R Antibody Picoband(r)A00070-3-CARRIER-FREE
ApplicationsWestern Blot, ELISA
ReactivityHuman
TargetIGF1R
  • SizePrice
Product group Antibodies
RayBiotech
Anti-IGF1R Antibody144-62454
ApplicationsImmunoFluorescence, Western Blot, ImmunoHistoChemistry
ReactivityHuman, Mouse, Rat
TargetIGF1R
  • SizePrice
Product group Antibodies
Biomatik
Igf1R Polyclonal AntibodyCAC10405
ApplicationsImmunoFluorescence, ELISA
TargetIGF1R
  • SizePrice
Product group Antibodies
Assay Genie
IGF1R AntibodyCAB0243
ReactivityHuman
TargetIGF1R
  • SizePrice
Formalin-fixed and paraffin-embedded human lung carcinoma tissue labeled with Rabbit Anti-IGF1R/CD221 Polyclonal Antibody, Unconjugated (bs-0227R) at 1:300 followed by conjugation to the secondary antibody and DAB staining
Product group Antibodies
References
Bioss
IGF1R Polyclonal AntibodyBS-0227R
ApplicationsFlow Cytometry
ReactivityBovine, Canine, Equine, Human, Mouse, Porcine, Rabbit, Rat, Sheep
TargetIGF1R
  • SizePrice
Western Blot analysis of Hela cells using IGF-IR Polyclonal Antibody
Product group Antibodies
Cusabio
IGF1R/INSR AntibodyCSB-PA003003
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
ReactivityHuman, Mouse, Rat
TargetIGF1R
  • SizePrice
Product group Antibodies
GeneTex
IGF1R alpha + beta antibodyGTX10729
ApplicationsWestern Blot, ELISA, Neutralisation/Blocking
ReactivityHuman
TargetIGF1R
  • SizePrice
IHC-P analysis of human gastric adenocarcinoma(A), colon adenocarcinoma(B), endometrial carcinoma(uterus)(C), ovary adenocarcinoma(D), lung squamous cell carcinoma(E), stomach epithelium mucosae(F) using GTX83067 IGF1R beta antibody [3C8B1].
Product group Antibodies
GeneTex
IGF1R beta antibody [3C8B1]GTX83067
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
ReactivityHuman
TargetIGF1R
  • SizePrice