IGFL3 (human) (Prod. No. AG-40B-0090) binds to its receptor IGFLR1 (human):Fc (human) (Prod. No. AG-40B-0087). Method: IGFLR1 (human):Fc was coated on an ELISA plate at 1microg/ml overnight at room temperature. IGFL-3 (human) or a negative control, Ome
IGFL3 (human) (rec.)
AG-40B-0090
Overview
- SupplierAdipoGen Life Sciences
- Product NameIGFL3 (human) (rec.)
- Delivery Days Customer10
- CertificationResearch Use Only
- Concentration0.1 mg/ml
- Estimated Purity>95%
- Protein IDQ6UXB1
- Protein NameInsulin growth factor-like family member 3
- Scientific DescriptionInsulin-growth factor-like gene family is a new family of proteins consisting of four proteins in humans (IGFL1 to 4) and one in mice (mIGFL). mIGFL is expressed in normal skin in mice and further upregulated during inflammation responses in skin or after skin wounding. In human only IGFL1 expression is increased in psoriatic skin samples. mIGFL and human IGFL1 and 3 interact with specificity and high affinity to a novel receptor named IGF-like family receptor 1 (formerly TMEM-149). Analysis of the amino acid sequence of IGFLR1 indicated that this receptor is likely a novel member of the TNF-R family. IGFLR1 is expressed most abundantly on mouse T cells, suggesting that mIGFL and IGFL1 produced in the skin may potentially exert regulatory functions on T cell responses. - Recombinant Protein. Human IGFL3 (aa 25-125) is fused at the N-terminus to a FLAG®-tag. Source: HEK 293 cells. Lyophilized. Contains PBS. Insulin-growth factor-like gene family is a new family of proteins consisting of four proteins in humans (IGFL1 to 4) and one in mice (mIGFL). mIGFL is expressed in normal skin in mice and further upregulated during inflammation responses in skin or after skin wounding. In human only IGFL1 expression is increased in psoriatic skin samples. mIGFL and human IGFL1 and 3 interact with specificity and high affinity to a novel receptor named IGF-like family receptor 1 (formerly TMEM-149). Analysis of the amino acid sequence of IGFLR1 indicated that this receptor is likely a novel member of the TNF-R family. IGFLR1 is expressed most abundantly on mouse T cells, suggesting that mIGFL and IGFL1 produced in the skin may potentially exert regulatory functions on T cell responses.
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352202