IHMT-PI3K-455
HY-149493
Overview
- SupplierMedChem Express
- Product NameIHMT-PI3K-455 [3047746-40-4]
- Delivery Days Customer14
- CertificationResearch Use Only
- Molecular FormulaC26H21F2N7O3
- Molecular Weight517.49
- Scientific DescriptionIHMT-PI3K-455 (Compound 15u) is a potent, selective, orally active PI3Kgamma/delta dual inhibitor with IC50s of 7.1 nM and 0.57 nM for PI3Kgamma and PI3Kdelta, respectively. IHMT-PI3K-455 suppresses the AKT phosphorylation. IHMT-PI3K-455 inhibits tumor growth by recruiting and activating more CD8+ killing T cells.IHMT-PI3K-455 is used in cancer research[1].
- SMILESCOC1=C(OC)N=CC(C2=NC3=CC(NC4=CC=CC(CNC(C5=C(F)C=CC=C5F)=O)=N4)=NN3C=C2)=C1
- UNSPSC12131703