Bio-Connect

IHMT-PI3K-455

HY-149493
MedChem Express
Molecular Weight517.49
Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    IHMT-PI3K-455 [3047746-40-4]
  • Delivery Days Customer
    14
  • Certification
    Research Use Only
  • Molecular Formula
    C26H21F2N7O3
  • Molecular Weight
    517.49
  • Scientific Description
    IHMT-PI3K-455 (Compound 15u) is a potent, selective, orally active PI3Kgamma/delta dual inhibitor with IC50s of 7.1 nM and 0.57 nM for PI3Kgamma and PI3Kdelta, respectively. IHMT-PI3K-455 suppresses the AKT phosphorylation. IHMT-PI3K-455 inhibits tumor growth by recruiting and activating more CD8+ killing T cells.IHMT-PI3K-455 is used in cancer research[1].
  • SMILES
    COC1=C(OC)N=CC(C2=NC3=CC(NC4=CC=CC(CNC(C5=C(F)C=CC=C5F)=O)=N4)=NN3C=C2)=C1
  • UNSPSC
    12131703