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IHR-1 [548779-60-8]

IHR-1 [548779-60-8]

T24159
TargetMol Chemicals
CAS Number548779-60-8
Product group Chemicals
Estimated Purity98.60%
Molecular Weight454.13
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    IHR-1 [548779-60-8]
  • Delivery Days Customer
    4
  • CAS Number
    548779-60-8
  • Certification
    Research Use Only
  • Chemical Name
    IHR-1
  • Estimated Purity
    98.60%
  • Molecular Formula
    C20H12Cl4N2O2
  • Molecular Weight
    454.13
  • Scientific Description
    IHR-1 is a Potent Smo antagonist (IC50 = 7.6 nM). Selectively inhibits Hedgehog signaling over Wnt and Notch signaling pathways. Blocks Smo accumulation in primary cilium in vitro.
  • Shelf life instruction
    3 years
  • SMILES
    Clc1ccc(Cl)c(c1)C(=O)Nc1ccc(NC(=O)c2cc(Cl)ccc2Cl)cc1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200