Bio-Connect

IK1 inhibitor PA-6 [500715-03-7]

HY-112544
MedChem Express
CAS Number500715-03-7
Product group Chemicals
Estimated Purity99.62
Molecular Weight492.61
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Overview

  • Supplier
    MedChem Express
  • Product Name
    IK1 inhibitor PA-6 [500715-03-7]
  • Delivery Days Customer
    9
  • CAS Number
    500715-03-7
  • Certification
    Research Use Only
  • Estimated Purity
    99.62
  • Molecular Formula
    C31H32N4O2
  • Molecular Weight
    492.61
  • Scientific Description
    IK1 inhibitor PA-6 (PA-6), a pentamidine analogue, is a selective and potent IK1 (KIR2.x ion-channel-carried inward rectifier current) inhibitor, with IC50 values of 12-15 nM for human and mouse KIR2.x currents. IK1 inhibitor PA-6 (PA-6) elevates KIR2.1 protein expression and induces intracellular KIR2.1 accumulation. IK1 inhibitor PA-6 (PA-6) has the potential to treat atrial fibrillation and arrhythmia[1][2][3].
  • SMILES
    N=C(C1=CC=CC=C1)NC2=CC=C(OCCCCCOC3=CC=C(NC(C4=CC=CC=C4)=N)C=C3)C=C2
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200