IK1 inhibitor PA-6 [500715-03-7]
HY-112544
CAS Number500715-03-7
Product group Chemicals
Estimated Purity99.62
Molecular Weight492.61
Overview
- SupplierMedChem Express
- Product NameIK1 inhibitor PA-6 [500715-03-7]
- Delivery Days Customer9
- CAS Number500715-03-7
- CertificationResearch Use Only
- Estimated Purity99.62
- Molecular FormulaC31H32N4O2
- Molecular Weight492.61
- Scientific DescriptionIK1 inhibitor PA-6 (PA-6), a pentamidine analogue, is a selective and potent IK1 (KIR2.x ion-channel-carried inward rectifier current) inhibitor, with IC50 values of 12-15 nM for human and mouse KIR2.x currents. IK1 inhibitor PA-6 (PA-6) elevates KIR2.1 protein expression and induces intracellular KIR2.1 accumulation. IK1 inhibitor PA-6 (PA-6) has the potential to treat atrial fibrillation and arrhythmia[1][2][3].
- SMILESN=C(C1=CC=CC=C1)NC2=CC=C(OCCCCCOC3=CC=C(NC(C4=CC=CC=C4)=N)C=C3)C=C2
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
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