IKKbeta-IN-1 [2410423-31-1]
HY-146723
CAS Number2410423-31-1
Product group Chemicals
Molecular Weight554.66
Overview
- SupplierMedChem Express
- Product NameIKKbeta-IN-1 [2410423-31-1]
- Delivery Days Customer10
- CAS Number2410423-31-1
- CertificationResearch Use Only
- Molecular FormulaC31H30N4O4S
- Molecular Weight554.66
- Scientific DescriptionIKKbeta-IN-1 is a potent and orally active IkappaB (IKK-beta) inhibitor with IC50 of 0.20 microM. IKKbeta-IN-1 can reduce PGE2 and TNF-alpha production in mouse macrophage cells. IKKbeta-IN-1 has the ability to protect mice against septic shock induced mortality[1].
- SMILESN#CC1=CC=C(OC2=CC=C(/C=C(SC(N3C4=CC=C(OCCCN5CCN(C)CC5)C=C4)=O)/C3=O)C=C2)C=C1
- UNSPSC12131703