IL-1 alpha, Human

MedChem Express

IL-1 alpha, Human

10

Research Use Only

98.0

IL1A

interleukin 1 alpha

hematopoietin-1; IL1; IL-1 alpha; IL-1A; IL1-ALPHA; IL1F1; interleukin-1 alpha; preinterleukin 1 alpha; pro-interleukin-1-alpha

Interleukin-1 alpha

IL-1 alpha is a ubiquitous and pivotal pro-inflammatory cytokine. IL-1 alpha is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. IL-1 alpha plays an important role in inflammation and bridges the innate and adaptive immune systems. IL-1 alpha mediates the activation of NF-kappa-B and the three MAPK pathways p38, p42/p44 and JNK pathways[1][4]. IL-1 alpha protein, Human is a recombinant protein consisting of 159 amino acids (S113-A271) and is produced by E. coli.

-20°C

41116100