IL-1 Receptor Type I (human):Fc (human) (rec.)
AG-40B-0024
Overview
- SupplierAdipoGen Life Sciences
- Product NameIL-1 Receptor Type I (human):Fc (human) (rec.)
- Delivery Days Customer10
- CertificationResearch Use Only
- Concentration1 mg/ml
- Estimated Purity>95%
- Protein IDP14778
- Protein NameInterleukin-1 receptor type 1
- Scientific DescriptionIL-1RI is the receptor for interleukin-1alpha (IL-1A), beta (IL-1B) and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappaB. Signaling involves formation of a ternary complex containing IL1RAP, leading the activation of TOLLIP, MYD88 and IRAK1 or IRAK2. - Protein. Human IL-1RI (interleukin-1 receptor type I) (aa 21-336) is fused at the C-terminus to the Fc portion of human IgG1. Source: HEK 293 cells. Endotoxin content: 95% (SDS-PAGE). IL-1RI is the receptor for interleukin-1alpha (IL-1A), beta (IL-1B) and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappaB. Signaling involves formation of a ternary complex containing IL1RAP, leading the activation of TOLLIP, MYD88 and IRAK1 or IRAK2.
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352202
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