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IL-11R alpha, Mouse (HEK293, His)

HY-P70860
MedChem Express
Protein IDQ64385
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    MedChem Express
  • Product Name
    IL-11R alpha, Mouse (HEK293, His)
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Protein IDQ64385
  • Protein Name
    Interleukin-11 receptor subunit alpha-1
  • Scientific Description
    IL-11R alpha (IL-11RA) is the IL-11 receptor subunit alpha and also acts as an agonist of IL-11. IL-11R alpha binds to IL6ST/gp130 on cell surfaces and induces signal transduction[1]. IL-11R alpha activates Jak family of tyrosine kinases, JAK1, JAK2, and TYK2[3]. IL-11R alpha induces proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells[4]. IL-11R alpha plays an important role in the progression and the differentiation of human gastric carcinomas[5]. IL-11R alpha Protein, Mouse (HEK293, His) is a recombinant protein with a His label that consists of 344 amino acids (S24-Q367) and is produced by HEK293 cells.
  • UNSPSC
    12352202

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