IL-11R alpha, Mouse (HEK293, His)

MedChem Express

IL-11R alpha, Mouse (HEK293, His)

10

Research Use Only

98.0

Il11ra1

interleukin 11 receptor subunit alpha 1

GP130, Il-11ra, Il11ra, Il11ra2, NR1, interleukin-11 receptor subunit alpha-1, IL-11 receptor subunit alpha-1, IL-11R subunit alpha-1, IL-11R-alpha-1, IL-11RA1, Il-11ra-alpha, NR-1, enhancer trap locus homolog 2, etl-2, interleukin 11 receptor, alpha chain 1, interleukin 11 receptor, alpha chain 2, locus 2, novel cytokine receptor 1

Interleukin-11 receptor subunit alpha-1

IL-11R alpha (IL-11RA) is the IL-11 receptor subunit alpha and also acts as an agonist of IL-11. IL-11R alpha binds to IL6ST/gp130 on cell surfaces and induces signal transduction[1]. IL-11R alpha activates Jak family of tyrosine kinases, JAK1, JAK2, and TYK2[3]. IL-11R alpha induces proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells[4]. IL-11R alpha plays an important role in the progression and the differentiation of human gastric carcinomas[5]. IL-11R alpha Protein, Mouse (HEK293, His) is a recombinant protein with a His label that consists of 344 amino acids (S24-Q367) and is produced by HEK293 cells.

-20°C

41116100