IL-18R alpha, Human (HEK293, Fc)

MedChem Express

IL-18R alpha, Human (HEK293, Fc)

10

Research Use Only

95.00

IL18R1

interleukin 18 receptor 1

CD218a, CDw218a, IL-18R-alpha, IL-18Ralpha, IL-1Rrp, IL18RA, IL18Ralpha2, IL1RRP, interleukin-18 receptor 1, CD218 antigen-like family member A, IL1 receptor-related protein, cytokine receptor, interleukin-18 receptor alpha

Interleukin-18 receptor 1

IL-18R alpha (interleukin-18 receptor alpha) is an interleukin receptor of the immunoglobulin superfamily. IL-18 forms a signalling complex with the IL-18 receptor alpha (Ralpha) and beta (Rbeta) chains at the plasma membrane, which induces multiple inflammatory cytokines[1]. IL-18R complex recruits the IL-1R- activating kinase and TNF- associated factor 6, which phosphorylates nuclear factor kbeta- inducing kinase, with subsequent activation of nuclear factor kbeta[2]. IL-18R alpha inhibits the production of IFN-gamma stimulated with the combination of rhIL-2 and rhIL-18[3]. IL-18R alpha Protein, Human (HEK293, Fc) is a recombinant protein with a Fc label that consists of 329 amino acids (M1-R329) and is produced by HEK293 cells.

-20°C

41116100